Ozonated Oil products (based on olive oil, sunflower oil or others) provide a variety of scientifically and medically proven health benefits (see references below). They are used in cosmetics, skin care, beauty care, medical / pharmaceutical, food and animal products.
Some of the main benefits and typical uses of Ozonated Oils include:
- Regenerates and repairs the skin helping the healing process
- Protects, moisturises and nourishes the skin
- Cleans and sterilizes the epidermis
- Improves blood circulation
- Controls and prevents the spread of germs in some skin conditions (seborrhoea, acne, ringworm, skin lesions).
- Reduces swelling and inflammation
- Improves cellular function and cellular memory
- Helps repair damaged skin conditions such as redness, bedsores, sunburn, wrinkles,
- Helps avoid the use of more aggressive medical treatments such as corticosteroid creams
- Aids in the healing processes reduces scarring, soothes sore muscles
- Reduces incidence of degenerative skin conditions
- Remedy for sunburn, wrinkles, insect bites and stings
- Infections of the sebaceous glands (sweat)
- Other uses: haemorrhoids, cuts and burns, skin yeast, tinea versicolor, dermatitis
How are Ozonated Oils made?
Ozonated Oils are made from lipid oxidation, a product of the reaction of ozone with fatty acids and other substrates contained in vegetable oils. These compounds have germicidal, immunostimulant and tissue repair activity, which is why they are being applied today as a new strategy for the treatment of infections and different pathologies.1-4
Ozone is a strong oxidiser which can kill microorganisms and viruses effectively. It has been used for treatment of water and wastewater since the early 1900s. Ozone has a very short life time and at room temperature. It returns to its oxygen state in less than a minute, limiting its use. This is where vegetable oils come in. When mixed with ozone it modifies the chemical structure of vegetable oils and allows the ozone to be stored in a stable and active manner for several years. 1-4
Through these ozone / vegetable oil chemical reactions, pharmacological active ingredients are produced with high added value without changing the rest of the molecule. The compounds that are formed when ozonising the oil are: ozonides, peroxides and aldehydes; all three are substances with proven germicidal properties.1-6 The physical properties of the oil allow it to penetrate places where other aqueous antibiotics do not reach, such as alveolitis in the root canals of the teeth.1-6
Since the late 1800s, the use of sunflower, coconut and cod liver oils has been described in patients with different conditions, mainly tuberculosis. The oils were prepared by enriching them with oxygen and exposing them to UV radiation from the sun.7
The applications for ozonated vegetable oil have spread rapidly. They have been used for the topical treatment of various diseases such as: skin infections, nail fungus, diabetic foot, parasitosis, papillomatosis, traumatic lesions, infected wounds, ulcers, eschar, herpetic lesions, fungal infections, insect bites, dermatitis, skin in an inflammatory phase due to atopic dermatitis, interdigital itching, psoriasis, vaginal infections and disorders, burns, and infectious stomatological conditions, among many others.7-25
Additionally, Ozonated Oils have other properties that are quite important: stability, long shelf life, tolerance, low surface tension, it is soluble in fat and does not dry out, thus preventing the formation of scabs and cracks.7,22
|Periodontal||Acute gingivitis Acute necrotizing ulcer gingivitis Periodontitis||Ozonated sunflower oil, topical application|
|Stomatological||Aphthous stomatitis Infected root canals Alveolitis||Ozonated sunflower oil, topical application|
|Venous insufficiency of the lower limbs||Varicose ulcers||Locally applied ozonated oil emulsion|
|Stomach / digestive system||Gastric ulcers Intestinal infections Giardiasis Helicobacter pylori Hemorrhoids Acute tonsillitis||Capsules, oral Capsules, oral Capsules, oral Capsules, oral Topical application Topical application|
|Dermatological||Acne Athlete´s foot (tinea pedis) Impetigo Onychomycosis Fistulas Surgical wounds Burns Pressure sores Folliculitis and bedsores Diabetic foot||Topical application|
|Ophthalmological||Conjunctivitis Corneal ulcers Keratitis Blepharitis Viral keratitis||Topical application|
|Gynecological||Human papillomavirus (HPV) Vaginal level and cervix (94% efficacy) Genital herpes Vulvovaginitis due to Candida Albicans||Application topically and ovules|
Why use concentrated ozone in an oil?
The answer is simple: many of the drugs that previously were efficient, have stopped giving the expected results. In some cases the doses have to be increased significantly and in others, the side effects are very harmful.
Are all vegetable oils useful in the preparation of Ozonated Oil?
Before answering this question, we could ask the following question: where do vegetable oils come from? They are a reserve food product and are necessary for plant cells to start the germination process of seeds inside some fruits.
Vegetable oils are mainly made up of triglycerides and, depending on their origin, their composition of saturated and unsaturated fatty acids can vary (Fig.2).26 All vegetable oils can, in principle, be ozonized. However, the reaction of ozone with vegetable oils occurs through the double bonds of unsaturated fatty acids (Fig.3). Hence the greater the number of double bonds available in the molecule, the greater the number of possible reactions with ozone and also the higher activity of the final product.
|Vegetable Oil||Saturated (%)||Monounsaturated (%)||Polyunsaturated (%)|
One of the oils that has given the best results, in terms of its antimicrobial activity, is sunflower seed oil.3,19 This is attributed, particularly, to the amount of polyunsaturated fats it contains.
Oils hold varying amounts of ozone depending on the oil, which can be measured. The Potential Ozonide Index (POI) is determined by measuring the Omega 3, 6, and 9 fatty acids in the oil. Oils with higher 9s hold more ozone. Each oil has a different amount of 3, 6, and 9 fatty acids and each fatty acid is weighed differently. Every one has its own unique benefits as well as different level of ozone saturation levels it can obtain. Coconut holds lower amounts of than other oils, making it ideal for those who want to use ozone but prefer lower levels of intensity, for example.
Below is a chart indicating the POI for some common vegetable oils. The Formula used is:
Omega 3 (x3) + Omega 6 (x2) + Omega 9 (x1) = POI
|Vegetable Oil||Omega 3||Omega 6||Omega 9||Strength (POI)|
What are the benefits of Ozonated Oil?
Some of the benefits of Ozonated Oil include:
- It is 100% organic.
- Does not require additives such as stabilizers, preservatives and colorants.
- In topical application it is activated by the body temperature releasing oxygen to the skin.
- The release process can take up to twelve hours or more (extended release).
- It is safe and non-toxic.
- It is one of the most advanced and proven products on the market. Ozonated Oil has been known since the 1800s. Many current patents have existed for 40 years.
- It is so stable that it can last indefinitely if kept refrigerated.
- Has similar or superior effects to traditional antibiotics.
- A broad antimicrobial spectrum
- A low rate of adverse events
- Lower cost compared to conventional treatments
What type of products are marketed using Ozonated Oil as the active ingredient?
Ozonated Oil products that are being marketed worldwide include: extracts, creams, ointments, gels, ovules, soft capsules and suppositories among others.
Ozonated Oils are also used extensively in the cosmetic market as the active ingredient for antibacterial soaps, deodorants (they do not require aluminum hydroxide), toothpastes, bath gels, anti-aging creams, regenerative creams and special creams (for normal, dry, sensitive and oily skin types).
Currently, there are a wide variety of products on the market for specific ailments and conditions that use Ozonated Oil as the main active ingredient. For example, to fight acne, since it acts directly against the propionibacterium acnes bacteria.
The application of Ozonated Oil has spread to many countries. Ozonated Oil is considered by many doctors around the world as an alternative of great value because not only does it replace a large number of medicines but it is also relatively low cost, compared to conventional therapies, making it quite attractive.
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